Quarterly Journal of Science and Practice
A. K. Vorontsov, Yu. A. Parkhisenko, E. F. Cherednikov, A. V. Klimashevich, S. V. Barannikov, A. V. Chernykh, A. A. Bezaltynnykh
Смоленский государственный медицинский университет, Смоленск, Россия; Воронежский государственный медицинский университет имени Н. Н. Бурденко, Воронеж, Россия; Московский клинический научно-исследовательский центр имени А. С. Логинова, Москва, Россия
The aim of the study was to develop a method of surgical hemostasis by the combined use of the hemostatic drug "Sur- gitamp" and the powdered sorbent "Molselect G-50", followed by packaging with a mesh endoprosthesis, and to evaluate its effective¬ness on a model of an extensive bleeding liver wound in pigs. Materials and methods. The studies were carried out on 36 healthy laboratory animals - a Large white pig. A model of a bleeding liver wound was reproduced for each animal. In the experimental group, surgical hemostasis of liver wounds was performed by tamponing the liver wound with "Surgitamp hemostatic gauze, followed by applications of "Molselect G-50" sorbent and packaging with strips of polypropylene mesh prosthesis. In the control group, hemostasis of experimental liver wounds was carried out by stitching the wound with a U-shaped suture until the edges of the wound converged. Results. Experimental studies have shown that the use of surgical hemostasis technology of experimental bleeding liver wounds with the use of "Surgitamp" hemostatic gauze in combination with the application of "Molselect G-50" sorbent and packaging with strips of polypropylene mesh prosthesis allows for reliable hemostasis of experimental bleeding liver wounds, reducing the time to stop experi¬mental bleeding from 435.0 (421.0-445.0) s to 315.0 (306.0-328.0) s (p < 0.0001), with a decrease in the frequency of repeated bleed¬ing from 33.3 to 5.5 % (p = 0.0408). Conclusion. The developed method of surgical hemostasis can be applied in clinical practice for extensive and deep liver damage.
abdominal trauma, liver ruptures, surgical hemostasis, granular sorbents
Show full text of article