Quarterly Journal of Science and Practice
A. A. Ozerov, M. S. Novikov
Волгоградский медицинский научный центр, лаборатория медицинской химии
The alkylation of 2-aminobenzimidazole with anilides of chloroacetic acid in anhydrous DMF at a temperature of 20– 100 °C in the presence of potassium carbonate leads to the formation of N1-substituted derivatives with the yield of 49– 74 %, and minor amounts of symmetric N1,N3-disubstituted analogues.
2-aminobenzimidazole, chloroacetanilide, N-alkylation
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