Volgograd Journal of Medical Research

Volgograd Journal of Medical Research

Quarterly Journal of Science and Practice


UDK: 616.61-091

Pathomorphological changes in the brain in experimental modeling of chronic ischemia

A. V. Smirnov, M. V. Schmidt, E. V. Berezin, V. S. Zamaraev, E. D. Lutaya

Волгоградский государственный медицинский университет; Волгоградский медицинский научный центр

Резюме

Comparative qualitative and quantitative structural analysis revealed pathological changes in the cerebral cortex, hippocampus, striopallidar system, cerebellum and brain stem in experimental modeling of ischemic encephalopathy by partial bilateral carotid artery stenosis. The most pronounced signs of damage, confirmed by significant changes in morphometric parameters, were found in the Purkinje neurons of cerebellum, as well as the neurons of some magnocellular nuclei of brain stem.

Ключевые слова

brain, ischemia, cerebellum, brain stem

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