Quarterly Journal of Science and Practice
A. I. Luganchenko, M. S. Novikov, A. A. Ozerov, G. Andrei, R. Snoeck
Волгоградский медицинский научный центр, лаборатория медицинской химии; Rega Institute for Medical Research, Leuven, Belgium
The interaction of equimolar amounts of 1,3-dibenzoyl uracil derivatives and p-toluenesulphonate of 2-(2- naphthyloxy)ethanol in the presence of excess of potassium carbonate in anhydrous DMF at room temperature for 24 h gives rise to 1-[2-(2-naphthyloxy)ethyl]-3-benzoyluracil derivatives. These compounds demonstrate moderate activity against varicella zoster virus in vitro compared to acyclovir.
dibenzoyluracil, toluenesulfonate, alkylation
Show full text of article