Quarterly Journal of Science and Practice
M. E. Statsenko, S. V. Turkina, N. N. Shilina, M. A. Kosivtsova, Y. E. Lopushkova, A. A. Vinnikova, B. A. Lempert, E. N. Zavodchikova
Волгоградский государственный медицинский университет, кафедра внутренних болезней педиатрического и стоматологического факультетов
The combination of chronic heart failure (CHF) and diabetes mellitus (DM) type 2 results in a higher prevalence as well as greater severity of target organ damage. Endothelial dysfunction plays an important role in the development and formation of pathological types of microcirculation in patients with chronic heart failure and diabetes mellitus type 2. The aim of our study was to investigate the features of the icrocirculation in patients with chronic heart failure and diabetes mellitus type 2. A large proportion of spastic type of microcirculation was found in patients with chronic heart failure and diabetes mellitus type 2. In the group of patients with isolated heart failure the hyperemic type of microcirculation prevailed. Higher indicators of peripheral tissue perfusion were observed in patients when heart failure was not associated with diabetes mellitus type 2. When interpreting the contribution of various components to the formation of a certain type of microcirculation, a greater role of the neurogenic component was registered in patients suffering from diabetes mellitus type 2. In patients with CHF not associated with diabetes mellitus the importance of myogenic and, to a lesser degree, endothelial components prevailed.
microcirculation, chronic heart failure, diabetes mellitus type 2
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