Quarterly Journal of Science and Practice
A. S. Taran, N. I. Cheplyaeva
Волгоградский государственный медицинский университет, кафедра фармакологии
The objective of this study was to assess the effect of vildagliptin and sitagliptin on the activity of dipeptidylpeptidase-4 by the methods of spectrophotometry and fluorometry using blood plasma and recombinant enzyme. The study showed that both methods can be used for screening substances with dipeptidylpeptidase-4.
dipeptidylpeptidase-4 inhibiting activity, sitagliptin, vildagliptin, hypoglycemic drugs.
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