Volgograd Journal of Medical Research

Volgograd Journal of Medical Research

Quarterly Journal of Science and Practice


UDK: УДК 651:547.466.3

ANALYTICAL FEATURES OF CHROMATOGRAPHIC METHOD OF QUANTITATIVE DETERMINATION OF GABA DERIVATIVES

L. A. Smirnova, I. N. Turenkov, V. N. Perfilova, A. F. Riabuha, E. A. Suchkov

Волгоградский государственный медицинский университет, лаборатория фармакокинетики НИИ фармакологии, кафедра фармакологии и биофармации ФУВ, лаборатория фармакологии сердечно-сосудистых средств НИИ фармакологии, ГУ ВМНЦ

Резюме

Analysis of current chromatographic methods of quantitative determination of GABA derivatives in biological samples was studied. Conditions of chromatographic analysis and extraction from biological samples providing optimal validation parameters were developed.

Ключевые слова

HPLC, quantitative determination, GABA derivatives.

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