Quarterly Journal of Science and Practice
O. Y. Grechko, N. V. Eliseeva, D. M. Chikun, A. A. Spasov, V. A. Anisimova
Волгоградский государственный медицинский университет, кафедра фармакологии
We studied the efficacy of RU-1203 compound exhibiting kappa-agonist activity with different routes of administration. It is established that the compound RU-1203 shows the greatest analgesic efficacy when administered intravenously; it is also active when administered orally, in contrast to butorphanol, the reference drug.
kappa-opioid receptor, agonist, opioid analgesics
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